论文部分内容阅读
目的分析影响肾病综合征口服激素治疗依从性的相关因素。方法依据Morisky标准评判90例肾病综合征患者激素治疗依从性情况,比较不同依从性患者的性别、年龄、居住地、接受教育时间、职业、肾病综合征病程、经济状态、报销医疗费、肾病综合征认知程度、心理反应、激素不良反应等因素。结果对肾病综合征随访8个月~2年,平均(14.26±3.22)个月,90例患者应用激素依从性好60例(66.67%),依从性差30例(33.33%),单因素检验年龄、居住地、接受教育时间、职业、肾病综合征病程、经济状态、报销医疗费、肾病综合征认知程度、心理反应、激素不良反应因素存在差异(P<0.05)。Logistic回归分析影响肾病综合征患者应用激素治疗依从性影响因素:年龄较大(OR=4.32,95%CI:2.68-29.26,疾病知识认识不足(OR=4.09,95%CI:2.06-23.17)、激素不良反应(OR=3.87,95%CI:1.80-19.40)、不良心理反应(OR=3.02,95%CI:1.91-25.23)。结论肾病综合征激素治疗依从性较差,影响因素复杂,应通过医护人员、家庭、患者的共同努力,减少肾病综合征患者不依从行为,使其积极配合治疗。
Objective To analyze the related factors influencing the adherence of oral hormones to nephrotic syndrome. Methods According to Morisky criteria, 90 patients with nephrotic syndrome were evaluated for their compliance with hormone therapy. Gender, age, place of residence, education time, occupation, duration of nephrotic syndrome, economic status, reimbursement of medical expenses, nephrology syndrome Sign cognition, psychological reaction, hormone adverse reaction and other factors. Results The nephrotic syndrome was followed up for 8 months to 2 years with an average of (14.26 ± 3.22) months. 90 patients had good compliance with hormone compliance (66.67%), 30 patients with poor compliance (33.33%), , Place of residence, time of education, occupation, course of nephrotic syndrome, economic status, reimbursement of medical expenses, cognition of nephrotic syndrome, psychological reaction and adverse effects of hormones (P <0.05). Logistic regression analysis showed that the influencing factors of hormone therapy compliance in patients with nephrotic syndrome were older age (OR = 4.32, 95% CI: 2.68-29.26, less understanding of disease knowledge (OR = 4.09, 95% CI: 2.06-23.17, (OR = 3.87, 95% CI: 1.80-19.40) and adverse psychological reaction (OR = 3.02, 95% CI: 1.91-25.23) .Conclusion The treatment of nephrotic syndrome has poor compliance and complicated factors, Through the joint efforts of medical staff, families and patients, patients with nephrotic syndrome can reduce their non-compliance and cooperate with them actively.