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近年来,经冠状动脉介入术(PCI)已经成为冠心病治疗的一个重要手段,其显著疗效亦被大规模的临床试验所证实。但球囊扩张术及传统金属裸支架植入术后,其中、短期内出现再狭窄的发生率达20-50%[1],严重限制了PCI的发展,其主要原因为血管壁弹性回缩、支架邻近血管重塑、炎症、血管内膜增生。
In recent years, percutaneous coronary intervention (PCI) has become an important means of treatment of coronary heart disease, and its significant effect has also been confirmed by large-scale clinical trials. However, balloon dilatation and conventional bare metal stent implantation, of which short-term restenosis occurs in the rate of 20-50% [1], severely limited the development of PCI, the main reason for the elastic retraction of the vessel wall , Stents adjacent to vascular remodeling, inflammation, intimal hyperplasia.