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[目的]比较腹腔镜肝切除术与射频消融术治疗小肝细胞癌的疗效及对患者生活质量的影响。[方法]收取小肝细胞癌患者79例作为研究对象,根据术式不同将其分为腹腔镜组(41例)和射频消融组(38例),分别采用腹腔镜肝切除术与射频消融术进行治疗。比较两组患者围手术期指标(手术时间、术中出血量、输血例数及住院时间)、治疗效果、术后疼痛评分、并发症以及生活质量恢复情况。[结果]射频消融组手术时间、术中出血量、输血例数及住院时间均显著低于腹腔镜组,差异具有统计学意义(P<0.05)。腹腔镜组总缓解率(85.37%)低于射频消融组(89.47%),但差异无统计学意义(P>0.05)。射频消融组疼痛VAS评分明显低于腹腔镜组,差异有统计学意义(P<0.05)。两组并发症无统计学差异(P>0.05)。射频消融组生活质量改善率(60.52%)明显高于腹腔镜组(31.71%),差异有统计学意义(P<0.05)。[结论]采用射频消融术治疗小肝细胞癌与腹腔镜肝切除术相比具有更好的临床疗效,利于减轻疼痛并提高患者生活质量。
[Objective] To compare the efficacy of laparoscopic hepatectomy and radiofrequency ablation in the treatment of small hepatocellular carcinoma and its impact on quality of life of patients. [Methods] A total of 79 patients with small hepatocellular carcinoma (HCC) were enrolled in this study. They were divided into laparoscopic group (41 cases) and radiofrequency ablation group (38 cases) according to different surgical procedures. Laparoscopic liver resection and radiofrequency ablation For treatment. Perioperative indexes (operative time, intraoperative blood loss, blood transfusion and hospital stay), therapeutic effect, postoperative pain score, complications and quality of life recovery were compared between the two groups. [Results] The operation time, intraoperative blood loss, blood transfusion and hospitalization time in radiofrequency ablation group were significantly lower than those in laparoscopic group, the difference was statistically significant (P <0.05). The total response rate of laparoscopic group (85.37%) was lower than that of radiofrequency ablation group (89.47%), but the difference was not statistically significant (P> 0.05). VAS score of radiofrequency ablation group was significantly lower than that of laparoscopic group, the difference was statistically significant (P <0.05). No significant difference between the two groups of complications (P> 0.05). The improvement rate of quality of life (60.52%) in radiofrequency ablation group was significantly higher than that in laparoscopic group (31.71%), the difference was statistically significant (P <0.05). [Conclusion] Radiofrequency ablation for small hepatocellular carcinoma has better clinical curative effect than laparoscopic hepatectomy, which will help relieve pain and improve patients’ quality of life.