β_2—微球蛋白(β_2—MG)自1968年由瑞典Berggard等从Wilson病和慢性镉中毒患者尿中分离纯化以来,研究人员对体液β_2—MG的含量进行了深入的研究.各种体液β_2—MG的测定具有不同的临床意义,对某些疾病的筛查及疗效判断具有重要的临床价值,现已广泛应用于临床.一、β_2—MG的测定和正常范围(一)、测定方法β_2—MG的测定有RIA、EIA、SRID等方法,但SRID方法与其他方法相比有高值倾向. β_2-MG (β_2-MG) Since 1968, Sweden Berggard, etc. from Wilson’s disease and chronic cadmium poisoning in patients with urine isolation and purification, the researchers of body fluid β_2-MG content were in-depth study of various body fluids β_2 -MG determination has different clinical significance, for some diseases screening and curative effect judgment has important clinical value, has been widely used in clinical.A determination of β_2-MG and the normal range (a), determination of β_2 -MG measured with RIA, EIA, SRID and other methods, but the SRID method compared with other methods have a high tendency.