冷凝集素综合症是由于体内冷抗体在37℃以下甚或低至20℃,使红细胞破坏增速所引起的一种自家免疫性溶血性疾病,国内外报导不多,因本症少见常延误诊断。为了提起临床注意,将我院所见一例报导如下: 刘某,男性,50岁,已婚,农民。河北省井陉县人。住院号:A-016834。因季节性头晕乏力10多年,近日加重,于1980年4月24日入院。素日头晕乏力,多在冬季或遇冷发病。1976年以来,每到冬季症状进行性加重,而于次年2月症状尤为明显,劳动时心慌气短,曾在当 Cold agglutinin syndrome is due to cold antibodies in the body even below as low as 20 ℃, so that the destruction of red blood cells caused by an increase of autoimmune hemolytic disease, few reports at home and abroad, due to the diagnosis of this disease is often delayed . In order to bring clinical attention, we will see a case of hospital reported as follows: Liu, male, 50 years old, married, farmer. Jingxing County, Hebei Province. Hospital number: A-016834. Due to seasonal dizziness, fatigue for more than 10 years, recently increased, in April 24, 1980 admission. Dizzy day and night, mostly in the winter or cold onset. Since 1976, every winter symptoms worsen, but in February next year, the symptoms are particularly obvious, when working hard and flustered, had been