肺癌已经成为人类癌症死亡的主要原因之一。在我国肺癌是发病率最高的癌症,且发病率和死亡率迅速增长。由于绝大多数肺癌的临床诊断已属晚期,其中50%以上的患者已不能手术[1],因此,肺癌的早期诊断显得尤为重要。近年来,随着分子生物学的蓬勃发展,已阐明肺癌的发生发展与多种基? Lung cancer has become one of the major causes of cancer death in humans. Lung cancer in our country is the highest incidence of cancer, and the rapid increase in morbidity and mortality. As most clinical diagnoses of lung cancer are advanced, more than 50% of them have been unable to operate [1]. Therefore, the early diagnosis of lung cancer is particularly important. In recent years, with the vigorous development of molecular biology, it has been clarified that the occurrence and development of lung cancer and a variety of base?