The intracellular iron transfer process is not well understood, and the identity of the iron transporter responsible for iron delivery to the secretory comp
Mammalian iron metabolism is delicately regulated by many modulators.Among them, hepcidin is the key hormone that negatively modulate iorn hemeostasis.Hepci
Iron is an essential metal involved in many fundamental biochemical processes within a living cell or organism.In mammals, ceruloplasmin and hephaestin, two
There are two general forms of sideroblastic anemia, namely congenital sideroblastic anemia (CSA) and acquired sideroblastic anemia.The CSAs are a group of
Background The bodys requirement for iron is different at different developmental stages.However, the molecular mechanisms of age-dependent iron metabolism
Mutations in the well known superoxide dismutase SOD1 are known to cause familial amyotrophic lateral sclerosis (fALS), a form of neurodegenerative diseases