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几种临床上长期应用的传统中草药,在远东包括日本发现具有抗癌作用。方剂十全大补汤(JTT)由10种植物药组成:黄芪、肉桂、熟地黄、白芍、川芎、白术、当归、人参、茯苓和甘草。长期以来均用于治疗贫血、厌食、虚弱及疲劳过度等疾病。近年来,不少报道认为,十全大补汤单用或与其它抗癌药合用均具有抗癌作用,有利于接受化疗或放疗的癌症患者身体状况的恢复。胸腺嘧啶脱氧核苷酸合成酶(TS)是一种通过催化脱氧尿苷酸(dUMP)甲基化,并伴随N~5,N~(10)—亚甲基四氢叶酸转化为7,8—二氢叶酸,参与脱氧胸苷酸(dTMP)全部合成途
Several traditional Chinese herbal medicines that have long been clinically applied have been found to have anti-cancer effects in the Far East including Japan. Prescription Shiquandabutang (JTT) consists of 10 botanicals: Astragalus membranaceus, Cinnamon, Rehmannia glutinosa, Radix Paeoniae Alba, Rhizoma Chuanxiong, Atractylodes macrocephala, Angelica, Ginseng, Poria and Licorice. It has long been used to treat diseases such as anemia, anorexia, weakness, and fatigue. In recent years, many reports suggest that Shiquan Dabu Decoction alone or in combination with other anti-cancer drugs has an anti-cancer effect and is beneficial to the recovery of the physical condition of cancer patients undergoing chemotherapy or radiotherapy. Thymine deoxynucleotide synthetase (TS) is a methylation catalyzed by deoxyuridine (dUMP) accompanied by the conversion of N~5,N~(10)-methylenetetrahydrofolate to 7,8 Dihydrofolate, involved in the full synthesis of deoxythymidine (dTMP)