血管生成主要包括内皮细胞的移动与增殖 ,它不仅存在于胚胎发育、黄体形成等生理过程 ,而且在许多病理过程如恶性肿瘤、风湿性关节炎、糖尿病视网膜病变、银屑病、创伤愈合中起重要作用。因此 ,血管生成与抑制的研究近年受到广为关注 ,特别是研究抑制血管生成为控制肿瘤生长和 Angiogenesis mainly includes the movement and proliferation of endothelial cells. It not only exists in physiological processes such as embryonic development and corpus luteum formation, but also plays an important role in many pathological processes such as malignant tumor, rheumatoid arthritis, diabetic retinopathy, psoriasis and wound healing Important role. Therefore, studies on angiogenesis and inhibition have drawn much attention in recent years, and in particular, studies on the inhibition of angiogenesis in order to control tumor growth and