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目的观察硝苯地平联合厄贝沙坦治疗2型糖尿病的临床效果。方法选取医院收治的2型糖尿病患者46例作为研究对象,随机分为观察组和对照组,每组23例。对照组采用常规治疗,观察组在常规治疗基础上采用硝苯地平和厄贝沙坦联合治疗。观察2组患者的治疗效果及不良反应情况。结果观察组治疗总有效率为87.0%,高于对照组的56.6%(P<0.05)。对照组未出现不良反应,观察组出现头晕1例,2组不良反应发生率比较差异无统计学意义(P>0.05)。结论硝苯地平联合厄贝沙坦治疗2型糖尿病,临床效果良好,治疗有效率较高,同时用药安全、可靠,值得临床推广应用。
Objective To observe the clinical effect of nifedipine combined with irbesartan in the treatment of type 2 diabetes mellitus. Methods Forty-six patients with type 2 diabetes treated in our hospital were selected as study subjects and randomly divided into observation group and control group, with 23 cases in each group. The control group with conventional treatment, the observation group on the basis of conventional treatment with nifedipine and irbesartan combination therapy. Two groups of patients were observed the treatment effect and adverse reactions. Results The total effective rate in observation group was 87.0%, which was higher than 56.6% in control group (P <0.05). There were no adverse reactions in the control group, 1 case of dizziness in the observation group, and no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Nifedipine combined with irbesartan in the treatment of type 2 diabetes mellitus has good clinical effect and high treatment efficiency. At the same time, the drug is safe and reliable, which is worthy of clinical application.