白细胞介素2(IL-2)是T 细胞生长因子,但除了维持T 细胞增殖以外,IL-2还可促进NK 活性、诱生LAK 细胞、促进B 细胞分泌抗体。这些功能是否由同一种受体介导,一直是一个令人感兴趣的问题。T 细胞经丝裂原或抗原激活后,细胞表面出现一种Tac 抗原,分子量为55KD,已证明这种p55蛋白就是IL-2受体。由于p55能结合IL-2,并且是在T 细胞激活时出现的,从而使人们相信p55就是介导IL-2生理作用的受体。但令人不解的是,在NK 细胞、LAK 细 Interleukin 2 (IL-2) is a T-cell growth factor, but in addition to maintaining T cell proliferation, IL-2 can also promote NK activity, induce LAK cells, and promote the secretion of antibodies by B cells. Whether these functions are mediated by the same receptor has been an interesting issue. T cells after mitogen or antigen activation, a Tac antigen on the cell surface, the molecular weight of 55KD, this p55 protein has been proved to be IL-2 receptor. Since p55 binds to IL-2 and occurs upon T-cell activation, it is believed that p55 is a receptor that mediates the physiological role of IL-2. But what is puzzling is that in NK cells, LAK is fine