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作者报道1例用溴隐亭(bromocriptine)治疗催乳素瘤引起严重的脑脊液鼻漏。患者男性,38岁,因右眼视力障碍、性欲减退半年就诊。查见右侧同侧偏盲,无溢乳,睾丸正常。血促黄体生成激素、促卵泡激素明显降低,睾丸素轻度降低,而血清催乳素可高达3,535(正常<18)μg/L。X线片见蝶鞍严重侵蚀,电子计算机断层扫描(CT)见肿瘤向鞍外扩展达海绵窦,左侧向上扩展到丘脑和基底节。给予溴隐亭15mg/d,分次服用,72h内视野出现显著改善而出院,继续用溴隐亭17.5mg/d。2
The authors report a case of severe chorionic fluid rhinorrhea with bromocriptine in the treatment of prolactinoma. The patient was a 38-year-old male patient who had been diagnosed with sight disorders and decreased libido in the right eye for six months. Check the right side of the same side of the hemianopia, no galactorrhea, testicular normal. Luteinizing hormone, follicle stimulating hormone, and testosterone were slightly reduced in blood, and serum prolactin levels were as high as 3,535 (normal <18) μg/L. Severe erosion of the sella was seen in X-rays. The computed tomography (CT) showed that the tumor expanded beyond the side of the saddle to the cavernous sinus and the left side extended to the thalamus and basal ganglia. Bromocriptine (15 mg/d) was administered in divided doses. Within 72 hours, there was a significant improvement in the visual field and the patient was discharged. He continued to use bromocriptine 17.5 mg/d. 2