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目的:评价依那普利联合用药治疗高血压合并糖尿病的临床疗效。方法:将医院2015年1月至2015年6月收治的130例高血压合并糖尿病患者作为研究对象,双盲法分为两组,每组65例,两组均给予降糖药物常规治疗,在此基础上,对照组给予依那普利治疗,观察组给予依那普利联合左旋氨氯地平治疗,回顾性分析两组临床治疗效果。结果:观察组治疗后血压水平以及血浆内皮素-1改善效果均明显优于对照组,治疗总有效率高于对照组,比较均具有统计学差异(P<0.05)。结论:依那普利联合左旋氨氯地平治疗高血压合并糖尿病可取得理想疗效,值得选择。
Objective: To evaluate the clinical efficacy of enalapril combination therapy in the treatment of hypertension and diabetes mellitus. Methods: A total of 130 hypertensive patients with diabetes mellitus admitted from January 2015 to June 2015 in our hospital were enrolled in this study. The double-blind method was divided into two groups, 65 cases in each group. Both groups were given routine antidiabetic drugs. Based on this, the control group was given enalapril, and the observation group was given enalapril combined with levamlodipine. The clinical effects of the two groups were retrospectively analyzed. Results: The blood pressure and plasma endothelin - 1 in the observation group were significantly better than those in the control group. The total effective rate was higher in the observation group than in the control group (P <0.05). Conclusion: Enalapril combined with levamlodipine in the treatment of hypertension with diabetes can achieve the desired effect, it is worth to choose.