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目的 :探讨声门上型喉癌声带不同活动情况下的组织病理学特点 ,为喉部分切除术提供理论依据。方法 :84例声门上型喉癌喉切除标本 ,经火棉胶包埋 ,制成连续切片 ,苏木精 伊红染色 ,光学显微镜下观察。结果 :声带固定 2 6例中杓状软骨、声门旁间隙下区以及两者同时受侵率分别为 4 6 .2 %、15 .4 %、38.5 % ;声带活动受限 30例中杓状软骨、声门旁间隙下区以及两者同时受侵率分别为 4 6 .7%、6 .7%、13.3% ;声带活动良好 2 8例中杓状软骨及声门旁间隙下区无受侵。声带固定、声带活动受限、声带活动良好 3组之间杓状软骨及声门旁间隙下区的受侵率差异有统计学意义 (P <0 .0 5 ) ;侵犯声门旁间隙下区的肿瘤均侵犯了喉室 ,声带活动受限及声带固定者中 ,肿瘤组织侵犯声门旁间隙下区占侵犯喉室比例分别为 4 0 .0 % (6 / 15 )、73.7% (14 / 19) ,两者之间差异有统计学意义 (P <0 .0 5 )。结论 :肿瘤侵犯杓状软骨及声门旁间隙下区是声门上型喉癌引起声带活动受限或固定的主要原因 ,观察声带活动及喉室的受侵情况 ,可为喉部分切除术提供参考依据。
Objective: To investigate the histopathological features of vocal folds of supraglottic laryngeal carcinoma under different activities and provide a theoretical basis for partial laryngectomy. Methods: Totally 84 cases of laryngectomy of supraglottic laryngeal carcinoma were embedded in fire cotton gum and made into serial sections. The hematoxylin and eosin staining were observed under optical microscope. Results: 26 cases of arytenoid cartilage fixed in the vocal cord, the subglottic space and the rate of concurrent invasion were 46.2%, 15.4% and 38.5% respectively. The vocal fold activity was limited in 30 cases Cartilage, subglottic space and the rate of simultaneous invasion of the two were 46.7%, 6.7%, 13.3%, respectively; vocal cord activity was good in 28 cases of arytenoid cartilage and subglottic space below Invasion Vocal cord fixation, vocal cord activity is limited, the vocal cord activity is good 3 groups between the arytenoid cartilage and glottic inferior space invasion rate was statistically significant (P <0. 05); invasion of the glottic lower space Of the tumor were violations of the throat, vocal cord activity is limited and the vocal cord immobilizer, tumor invasion of the glottic area under the glottic invasion of the throat area accounted for 40.0% (6/15), 73.7% (14 / 19), the difference between the two was statistically significant (P <0. 05). CONCLUSIONS: Tumor invasion of the arytenoid cartilage and subglottic space is a major cause of supraglottic laryngeal cancer that causes limited or fixed vocal cord activity. Vocal cord activity and the invasion of the throat can be observed to provide a partial laryngectomy Reference.