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1977年Takatsukt 首次在日本发现成人T细胞白血病人后,接着其它学者相继证实此病的存在。在日本西南部的冲绳岛,病人出生的地理景观是成人T细胞白血病最显著的特征。 1980年发现了新的能与病人血清起反应的病毒,取名为成人T细胞白血病病毒(ATLA)。在成人T细胞白血病的流行地区,健康人群血中抗-ATLA阳性者(包括病人和健康人群)外周血T细胞带有ATLV。世界各地开展了抗ATLV抗体血清流行病学调查。然而,在日本的流行地区,却
After Takatsukt first discovered adult T-cell leukemia in Japan in 1977, other researchers confirmed the existence of the disease. In Okinawa, southwestern Japan, the geographic landscape from which patients were born is the most prominent feature of adult T-cell leukemia. In 1980, a new virus that reacted with the patient’s serum was found, named adult T-cell leukemia virus (ATLA). In the prevalence area of adult T-cell leukemia, peripheral blood T cells from anti-ATLA-positive (including patient and healthy) blood in healthy individuals carry ATLV. Serological epidemiology of anti-ATLV antibodies has been developed around the world. However, in the popular area of Japan, however