本文报告上海华山医院1952～1977年诊治的垂体嫌色细胞瘤409例的临床表现、诊断和治疗,其中305例经手术病理证实。全组409例中,男性240例,女性169例,男女之比为1.43∶1。发病年龄22月～69岁,21～50岁者占86.1%。病程3周～19年,平均约3年。临床表现(1)眼部表现:视力减退者327例(80%),双眼视力同时减退者223例(68.2%),视野缺损者316例(77.3%),双 This paper reports the clinical manifestations, diagnosis and treatment of pituitary chromophobe 409 cases diagnosed and treated at Shanghai Huashan Hospital from 1952 to 1977, of which 305 cases were confirmed by pathology. Of the 409 cases in the entire group, 240 were males and 169 were females. The ratio between males and females was 1.43:1. The age of onset was 22 months to 69 years, and people aged 21 to 50 years accounted for 86.1%. The disease duration ranged from 3 weeks to 19 years and averaged about 3 years. Clinical manifestations (1) Ocular performance: 327 cases (80%) with decreased visual acuity, 223 cases (68.2%) with simultaneous binocular vision loss, 316 cases (77.3%) with visual field defect, double