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儿童胰岛素依赖性糖尿病并发脑水肿是治疗酮症酸中毒的一种致命性合并症。文献复习17例儿童糖尿病酮症酸中毒于治疗中发生脑水肿,14例死亡。作者报告1例因糖尿病酮症酸中毒应用小剂量胰岛素持续滴注而发生脑水肿,经立即静脉输入甘露醇洽愈。患者为13岁男孩,因10天来多尿,3天来烦渴,数月内体重减轻11kg而入院。尿化验酮体强阳性,尿糖定量2g/dl以上,血糖400～800mg/dl(手指毛细血管法(?),乃给予正规胰岛素5μ静注,继之按0.1μ/kg/小时,持续静脉点滴(4μ/小时)。2小时后患儿共接受正规胰岛素7.4μ和1,600ml的静脉输液,排
Children with insulin-dependent diabetes mellitus and brain edema is a fatal complication of ketoacidosis. Literature review of 17 cases of children with diabetic ketoacidosis in the treatment of cerebral edema, 14 patients died. The authors report a case of cerebral edema caused by the sustained use of low-dose insulin in patients with diabetic ketoacidosis. Mannitol was administered immediately after intravenous infusion. The patient was a 13-year-old boy who had been hospitalized for urination for 10 days, polydipsia for 3 days and weight loss of 11 kg for several months. Urinary test ketone body strong positive urine glucose 2g / dl above, blood sugar 400 ~ 800mg / dl (finger capillary method (?), Is given regular insulin 5μ intravenous injection, followed by 0.1μ / kg / Drip (4μ / h) .2 hours after receiving a total of children with formal insulin 7.4μ and 1,600ml intravenous infusion, row