论文部分内容阅读
目的 :探讨窒息新生儿甲状腺功能的变化。方法 :对 117例窒息新生儿 (窒息组 )及 117例同期出生的正常新生儿 (对照组 )于出生第 1天及第 8天取静脉血检测T3 、T4、FT3 、FT4和TSH。结果 :窒息新生儿T3 、T4、FT3 、FT4均显著低于对照组 (P <0 .0 1或P <0 .0 5 ) ,重度窒息新生儿T3 、T4、FT3 、FT4均显著低于轻度窒息新生儿 (P <0 0 1或P <0 0 5 ) ,TSH无显著差异 (P >0 .0 5 ) ,第 8天复查T3 、T4、FT3 、FT4和TSH窒息组与对照组无显著差异 (P >0 .0 5 )。结论 :窒息新生儿甲状腺功能损害严重 ,且与窒息程度正相关 ,恢复后甲状腺功能自行恢复 ,无需甲状腺素治疗
Objective: To investigate the changes of thyroid function in neonates with asphyxia. Methods: Venous blood samples of T3, T4, FT3, FT4 and TSH were collected from 117 neonates with asphyxia (asphyxia group) and 117 normal newborn infants (control group) born on the first and eighth days of life. Results: The levels of T3, T4, FT3 and FT4 in neonates with asphyxia were significantly lower than those in control group (P <0.01 or P <0.05). T3, T4, FT3 and FT4 in newborn infants with asphyxia were significantly lower than those in mild (P0.05 or P0.05), no significant difference was found between TSH and neonatal asphyxia neonates (P0.05 or P0.05), and the levels of T3, T4, FT3, FT4 and TSH asphyxia group were not significantly different from the control group on the 8th day Significant difference (P> 0.05). Conclusion: Asphyxia neonates have severe thyroid function damage and are positively correlated with the degree of asphyxia. After thyroid function recovery, the thyroid function regains itself without thyroid hormone treatment