镍铬、金合金烤瓷牙修复后不同时期龈沟液IL-8含量水平探讨

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目的:探讨金合金、镍铬烤瓷牙修复对牙周组织的影响。方法:选取我院2011年5月~2012年5月期间的80例前牙缺损患者,根据修复内冠材料不同将其分为金合金组、镍铬合金组,观察不同时期天冬氨酸转氨酶(AST)、IL-8水平、龈沟液量(GCF)、碱性磷酸(ALP)。结果:修复后1周,两种合金烤瓷在龈沟液量、IL-8总量上与修复前比较,具有统计学意义;修复后3、6个月时,金合金组上述指标明显下降,至6个月时逐渐恢复至修复前水平,而镍铬合金组上述指标在修复6个月时与修复前比较,具有统计学意义,金合金组在修复3、6个月时,上述指标明显低于镍铬合金组;在IL-8含量上,两种合金烤瓷仅在修复3个月时有统计学差异,修复6个月时,两种金属烤瓷均恢复至修复前水平;镍铬合金组修复6个月时AST、ALP与修复前比较均存在明显差异,而金合金组在修复6个月时,AST水平也比修复前显著提高,在ALP上,修复6个月时,金合金组与健康牙差异不大。结论:金合金对牙龈的刺激较小,是烤瓷压内冠的理想材料。 Objective: To investigate the effect of gold alloy and Ni-Cr porcelain restoration on periodontal tissue. Methods: Eighty cases of anterior teeth defect from May 2011 to May 2012 in our hospital were divided into gold alloy group and nickel-chromium alloy group according to the different material of the restoration inner crown. The changes of aspartate aminotransferase (AST), IL-8 level, gingival crevicular fluid (GCF) and alkaline phosphatase (ALP). Results: One week after the repair, the two kinds of porcelain enamel in gingival crevicular fluid volume, IL-8 total volume compared with before repair, with statistical significance; 3,6 months after repair, the gold alloy group of the above indicators decreased significantly , And gradually returned to the pre-repair level at 6 months. However, the above indexes of Ni-Cr alloy group were statistically significant at 6 months of repair compared with those before repair, and at the 3 and 6-month restoration of gold alloy group, Significantly lower than the nickel-chromium alloy group; in the IL-8 content, the two kinds of alloy porcelain only at 3 months after repair was statistically significant, 6 months repair, the two kinds of metal porcelain were restored to the pre-repair level; At 6 months after repair, the levels of AST and ALP in the nickel-chromium alloy group were significantly different from those before the repair, while the levels of AST in the gold alloy group were also significantly higher than those before the repair at 6 months of repair. At 6 months after repair, , Gold alloy group and healthy teeth difference is not big. Conclusion: The gold alloy is less irritating to the gums and is an ideal material for porcelain crowns.
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