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目的探讨微波治疗联合外涂咪喹莫特乳膏治疗HIV/AIDS合并肛门尖锐湿疣的效果。方法对110例HIV/AIDS合并肛门尖锐湿疣患者治疗前进行血清CD4+T淋巴细胞数量和HIV-RNA载量检测,采用微波治疗1周后外涂咪喹莫特乳膏联合治疗,每4周复诊一次,如有复发重复治疗,并进行末次治疗后4个月的随访。结果在CD4+T淋巴细胞数量≥350×106/L的HIV患者中,20周时的治愈率为89.55%(60/67),CD4+T淋巴细胞数量<350×106/L的患者治愈率为72.09%(31/43)。结论 HIV/AIDS合并肛门尖锐湿疣治疗后易复发,在CD4+T细胞数量≥350×106/L患者中,微波结合咪喹莫特乳膏外涂治疗时间短,复发率低。
Objective To investigate the effect of microwave treatment combined with imiquimod cream on HIV / AIDS with condyloma acuminatum. Methods Totally 110 patients with HIV / AIDS complicated with condyloma acuminatum were enrolled in this study. Serum CD4 + T lymphocyte count and HIV-RNA load were detected before treatment. After 1 week of microwave treatment, imiquimod cream was applied to the patients and the treatment was repeated every 4 weeks , If recurrence of repeat treatment, and the last treatment after 4 months of follow-up. Results The cure rate was 89.55% (60/67) at 20 weeks and CD4 + T lymphocytes <350 × 106 / L in HIV patients with CD4 + T lymphocytes> 350 × 106 / L 72.09% (31/43). Conclusion HIV / AIDS complicated with anal condyloma acuminatum is easy to relapse after treatment. In the patients with CD4 + T cell count≥350 × 106 / L, microwave combined with imiquimod cream has a short treatment time and low recurrence rate.