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目的通过监测结果分析,掌握龙游县肾综合征出血热(HFRS)流行规律,有针对性地采取防控措施。方法对2004-2010年HFRS疫情资料进行分析,并采用现场调查与实验室检测相结合,开展人间疫情与宿主动物带病毒监测。结果龙游县2004-2010年HFRS年平均发病率为0.78/10万,患者以40～50岁为主,占63.64%,农民占77.27%,男女比例为2.14:1。季节高峰呈夏季和冬季的双峰型,全县多个乡(镇)均有发病,以龙南山区发病率最高。患者诊断符合率为82.35%。鼠类带病毒率为2.95%,室内以黄胸鼠为优势种,占80.28%;室外以黑线姬鼠为优势种,占89.29%。鼠血清HFRS抗体阳性率为4.81%。结论龙游县HFRS发病率呈现下降趋势,但流行特征并未发生明显改变。监测结果显示,龙游县是以姬鼠型为主的混合型HFRS疫区。
Objective To monitor the prevalence of hemorrhagic fever with renal syndrome (HFRS) in Longyou County through monitoring results and to take targeted prevention and control measures. Methods The data of epidemic situation of HFRS from 2004 to 2010 were analyzed, and the combination of field investigation and laboratory test were used to carry out the surveillance of human epidemic and host animal virus. Results The average annual incidence of HFRS from 2004 to 2010 in Longyou County was 0.78 / 100,000. The prevalence of HFRS in Longyou County was 63.64% with the age of 40-50 years. The average incidence of HFRS was 77.27%. The ratio of male to female was 2.14: 1. Peak season showed a summer and winter bimodal, the county multiple townships (towns) have onset, the highest incidence of mountainous area in South Longnan. The diagnosis rate of patients was 82.35%. The rate of rodent virus was 2.95%. The dominant species was Rattus flavipectus, accounting for 80.28% of the total. The dominant species of Apodemus agrarius was 89.29%. The positive rate of rat serum HFRS antibody was 4.81%. Conclusion The incidence of HFRS in Longyou County shows a downward trend, but the epidemic characteristics have not changed significantly. Monitoring results show that Longyou County is mainly based on the type of mixed-type HFRS epidemic.