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目的 :探讨乳腺导管原位癌 (ductalcarcinomainsitu ,DCIS)的发病趋势及治疗模式的变化。方法 :以 1982～ 1995年Hartford医院诊治的 4 79例乳腺DCIS病人为研究对象 ,进行回顾性分析研究。结果 :乳腺DCIS占全部乳腺癌的比例由 1982年的 3 30 %上升到 1995年的 17 35% ,这种趋势发生在 4 0岁以上的各年龄组中且上升最明显的年龄组是 4 0～ 4 9岁。乳腺DCIS病人的治疗模式中 ,乳腺切除术由 10 0 .0 0降至 2 1 95% ,局部切除术辅以放射治疗或者单纯局部切除术由 0 .0 0上升至 78 0 5%。结论 :近 2 0年来 ,乳腺DCIS的发病较前明显增多 ,其发病年龄趋于年轻化。乳腺DCIS的常用治疗方法是保守手术辅以术后放射治疗
Objective: To investigate the incidence of ductal carcinoma in situ (DCIS) and the changes of the treatment model. Methods: A total of 479 breast DCIS patients diagnosed and treated at Hartford Hospital from 1982 to 1995 were studied retrospectively. RESULTS: The proportion of breast DCIS in all breast cancers increased from 30% in 1982 to 17 35% in 1995. This trend occurred in all age groups over 40 years old, and the most significant increase was 40%. ~ 4 years old. In breast cancer patients with DCIS, mammectomy was reduced from 100.0% to 219.5%, and local resection combined with radiation therapy or simple local resection increased from 0.0 to 78.5%. Conclusion : In the recent 20 years, the incidence of DCIS in breast has increased significantly compared with that before. The age of onset tends to be younger. The common treatment for breast DCIS is conservative surgery supplemented with postoperative radiation therapy