论文部分内容阅读
The Keap1–Nrf2–ARE pathway is an important antioxidant defense mechanism that protects cells from oxidative stress.The homodimeric Keap1 protein functions as a redox sensor for environmental stress conditions and serves as a negative regulator of the transcription factor Nrf2 and ARE-controlled cytoprotective proteins.Under basal conditions,Nrf2 is bound to
The Keap1-Nrf2-ARE pathway is an important antioxidant defense mechanism that protects cells from oxidative stress. The homodimeric Keap1 protein functions as a redox sensor for environmental stress conditions and serves as a negative regulator of the transcription factor Nrf2 and ARE-controlled cytoprotective proteins .Under basal conditions, Nrf2 is bound to