目的:探讨奥曲肽治疗非胃底食管静脉曲张破裂所致上消化道大出血的临床疗效。方法:59例患者先给予奥曲肽 0．1 mg iv,再用奥曲肽0．1 mg持续静滴94～96 h,出血控制后逐步减量。结果:59例患者中仅3例无效,其余56例均在72 h 内止血,止血率达94．92％。结论:奥曲肽治疗非胃底食管静脉曲张所致上消化道大出血有较显著疗效。 Objective: To investigate the clinical efficacy of octreotide in treating upper gastrointestinal hemorrhage caused by non-gastric esophageal varices. Methods: Fifty-nine patients were given 0.1 mg iv of octreotide first, followed by intravenous infusion of 0.1 mg octreotide for 94-96 h. The amount of octreotide was gradually reduced after controlled bleeding. Results: Only 59 of the 59 patients were ineffective, and the remaining 56 patients stopped bleeding within 72 hours with a rate of 94.92%. Conclusion: Octreotide treatment of non-gastric esophageal varices caused by upper gastrointestinal bleeding more significant effect.