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应用琼脂糖-纤维蛋白-平板法和抗尿激酶多克隆抗体的免疫阻断法测定15名正常生育男子和20例精液液化不良的不育症男子精浆中尿激酶的活力。结果发现:正常生育组精浆中尿激酶的含量为8450±1050IU/L,液化不良组尿激酶的含量为6450±1050IU/L。与正常生育组比较,尿激酶活性明显降低,两组间差异有极显著性(P<0.001)。提示精浆中尿激酶可能与精液的液化有关联。
The activity of urokinase in 15 normal fertile men and 20 infertile men with seminal fluid liquefaction was measured by using the agarose-fibrin-plate method and anti-urokinase polyclonal antibody. The results showed that the content of urokinase in normal fertility group was 8450 ± 1050 IU / L, and that of liquefied poor group was 6450 ± 1050 IU / L. Compared with normal fertility group, urokinase activity was significantly lower, the difference between the two groups was extremely significant (P <0.001). Tip Seminal plasma urokinase may be associated with liquefaction of semen.