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作者为了解肾功能不全(renal insufficiency,RI)患者的上消化道粘膜变化特征,对19例正在接受血液透析的慢性 RI 患者进行了内镜观察及活组织检查。方法 RI 组19例中男15例,女4例,年龄35～64岁。血液透析时间1个月～12年,平均5年10个月。另设对照组16例,年龄、性别相仿。用内镜依次观察食管、胃及十二指肠球部,并分别于十二指肠球部、胃窦部、胃角部、胃体下部及胃体上部小弯侧进行活检。标本经 HE、PAS 染色后进行观察。结果一、血清胃泌素:RI 组245.0±166pg/ml,对照组为136.0±57.0pg/ml。
To understand the features of upper gastrointestinal mucosal changes in patients with renal insufficiency (RI), the authors performed endoscopic observation and biopsy of 19 chronic RI patients undergoing hemodialysis. Methods There were 19 males and 4 females in the RI group, aged 35-64 years old. Hemodialysis time is 1 month to 12 years, with an average of 5 years and 10 months. A separate control group of 16 patients was used, with similar age and gender. The endoscope was used to observe the esophagus, stomach, and duodenum, and biopsy was performed on the duodenal bulb, antrum, gastric horn, lower body of the stomach, and small curvature of the upper part of the body. Specimens were observed after staining with HE and PAS. Results 1. Serum gastrin: RI group was 245.0±166 pg/ml, and control group was 136.0±57.0 pg/ml.