采用正负交变加速度旋转刺激制备大鼠运动病模型。对运动病大鼠脑细胞Ｎａ＋Ｋ＋ＡＴＰａｓｅ、碱性磷酸酶和细胞色素氧化酶活性变化进行图像定量分析。结果表明，运动病大鼠大脑皮质、小脑皮质和脑干前庭区脑细胞Ｎａ＋Ｋ＋ＡＴＰａｓｃ和细胞色素氧化酶活性明显降低，而碱性磷酸酶活性明显升高。提示运动病的发生与中枢神经细胞有氧代谢、细胞膜通透性和钠、钾离子交换有关 Rat model of motion sickness was made by rotational stimulation of positive and negative alternating acceleration. Quantitative image analysis of Na +  K +  ATPase, alkaline phosphatase and cytochrome oxidase activity in brain cells of rats with motion sickness. The results showed that the activity of Na + K +  ATPase and cytochrome oxidase in cerebral cortex, cerebellar cortex and vestibular area of ​​brainstem of rats with motion sickness was obviously decreased, while the activity of alkaline phosphatase was obviously increased. Tip motion sickness and central nervous cell aerobic metabolism, cell membrane permeability and sodium, potassium ion exchange