论文部分内容阅读
目的重新认识氯霉素对小儿恙虫病的临床作用。方法对近5年收治的153例小儿恙虫病分成不伴多器官功能损害组和伴多器官功能损害组,应用氯霉素和阿奇霉素治疗,进行临床分析。结果不伴多器官功能损害组,氯霉素和阿奇霉素疗效无差异;伴多器官功能损害组,氯霉素较阿奇霉素效果显著。差异有统计学意义。结论轻症病例,可首选大环内酯类抗生素,如阿奇霉素治疗,如患儿并多器官功能损害,则应果断应用氯霉素以达到迅速起效,以免延误治疗,导致病情加重或出现更多的并发症,错过治疗机会。传统药物氯霉素在小儿恙虫病的治疗中仍处在不可被替代的地位。
Objective To re-recognize the clinical role of chloramphenicol in pediatric scrub typhus. Methods A total of 153 cases of pediatric scrub typhus treated in the recent 5 years were divided into groups without multiple organ dysfunction and with multiple organ dysfunction. Chloramphenicol and azithromycin were given for clinical analysis. Results without multiple organ dysfunction group, chloramphenicol and azithromycin no difference; with multiple organ dysfunction group, chloramphenicol more than azithromycin significant effect. The difference was statistically significant. Conclusions Mild cases of macrolide antibiotics, such as azithromycin, such as children with multiple organ dysfunction, you should decisively apply chloramphenicol in order to achieve rapid onset, so as not to delay treatment, leading to exacerbations or more Many complications, missed treatment opportunities. Chloramphenicol traditional medicine in the treatment of pediatric scrub typhus is still in an irreplaceable position.