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目的：观察大鼠在不同模拟高度下几种微量营养素状态的变化。方法：成年大白鼠按模拟实验高度分４组，采取股动脉放血致死，收集血液样品，测定全血谷胱甘肽还原酶活性系数（ＢＧＲ－ＡＣ值）、全血转羟乙醛酶活性（ＴＰＰ数应）、全血Ｖｃ、血清ＶＥ及血清微量元素Ｚｎ、Ｃｕ、Ｆｅ、Ｍｎ等。结果：随着高度的上升，大鼠全血ＢＧＲ－ＡＣ值有上升趋势，０～４０００ｍ差别显著，但４０００～８０００ｍ差别不显著。ＴＰＰ效应在６０００ｍ以下差别均显著。随高度上升血清Ｖｃ和ＶＥ有下降趋势，微量元素Ｚｎ、Ｆｅ也下降，Ｚｎ最明显，Ｍｎ则上升，Ｃｕ变化不明显。结论：海拔越高营养素需要量越大
Objective: To observe the changes of several micronutrients in rats under different simulated heights. Methods: The adult rats were divided into 4 groups according to the height of the simulated experiment. Blood samples were collected from the femoral artery to determine the activity of glutathione reductase (BGR-AC), whole blood glucose TPP should), whole blood Vc, serum VE and serum trace elements Zn, Cu, Fe, Mn and so on. Results: The BGR-AC of whole blood increased with the increase of altitude, but the difference was significant at 0 ~ 4000m, but the difference was not significant at 4000 ~ 8000m. TPP effect in 6000m the following differences were significant. With the increase of serum Vc and VE there is a downward trend, trace elements Zn, Fe also decreased, Zn most obvious, Mn increased, Cu change was not obvious. Conclusion: The higher the elevation, the greater the nutrient requirement