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本组息肉患者494例,癌变者101例,随着息肉的增大,其癌变率也增加。恶变息肉主要分布在直肠(57.4%),次为乙状结肠(19.8%)。管状腺瘤瘤体较小,恶变率较低,绒毛型腺瘤瘤体较大,恶变率较高,且呈重度不典型增生多见。单发息肉癌变率13.1%,2-5个息肉者癌变率24.4%,6个以上者癌变率38.0%,腺瘤病12例全部癌变。息肉癌变时间1至15年。癌变术后标本病理均见癌旁组织残存良性管状腺瘤或绒毛型腺瘤成份,从组织学上证明了息肉癌变过程。
There were 494 cases of polyposis and 101 cases of cancer in this group. With the increase of polyps, the rate of canceration also increased. The malignant polyps were mainly distributed in the rectum (57.4%), followed by the sigmoid colon (19.8%). Tubular adenoma tumor is smaller, malignant transformation rate is lower, villous adenoma tumor is larger, malignant transformation rate is higher, and severe dysplasia is more common. The rate of malignant transformation of single polyposis was 13.1%, the cancerous rate of 2-5 polyps was 24.4%, the cancerous rate of 6 or more polyps was 38.0%, and 12 cases of adenomatosis were all cancerous. Polyposis cancer time 1 to 15 years. After pathological changes of cancerous specimens, benign tubular adenomas or villous adenomas were found in adjacent tissues, which proved histologically the polyposis.