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Purpose:Lens coloboma is a rare congenital disorder of crystalline lens characterized by notching of the equator of the lens.Coloboma can occur in isolation or with other ocular malformations. The authors reported 5 cases of lens coloboma associated with some ocular malformations. Methods:Case reports.The clinical features,imaging findings and associated ocular malformations were reported. Results:One case was not associated with ocular anomalies. One patient was involved with iris and choroid coloboma;another subject suffered from total cataract;and the fourth patient was affected by lens dislocation.The remaining case included aniridia. The pathogenic mechanisms and relationship of the ocular malformations have been discussed. Conclusion:Lens coloboma can be associated with other ocular malformations, such as iris coloboma, choroid colobma, localized or total caratact.
Purpose: Lens coloboma is a rare congenital disorder of the crystalline lens characterized by notching of the equator of the lens. Coloboma can occur in isolation or with other ocular malformations. The authors reported 5 cases of lens coloboma associated with some ocular malformations. Methods: Case reports. The clinical features, imaging findings and associated ocular malformations were reported. One case was not associated with ocular anomalies. One patient was involved with iris and choroid coloboma; another subject from from total cataract; and the fourth patient was affected by Lens dislocation. The remaining case included aniridia. The pathogenic mechanisms and relationship of the ocular malformations have been discussed. Conclusion: Lens coloboma can be associated with other ocular malformations, such as iris coloboma, choroid colobma, localized or total caratact.