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为了探讨庚型肝炎病毒（ＨＧＶ）感染的肝组织病变特征，对１８例单纯ＨＧＶＲＮＡ和（或）抗体阳性患者活检肝组织作光、电镜观察。结果显示：１８例ＨＧＶ感染肝组织均呈急性或轻度慢性病毒性肝炎改变，表现为肝细胞肿胀，线粒体扩张，嵴减少或消失，粗面内质网扩张及核蛋白颗粒脱失；汇管区和肝小叶内轻度炎细胞浸润。观察结果表明：ＨＧＶ致肝炎病变可能明显轻于Ａ－Ｅ型肝炎。
In order to investigate the liver lesions of patients with hepatitis G virus (HGV) infection, liver biopsies from 18 patients with HGV RNA and / or antibody positive were examined by light and electron microscopy. The results showed that all the 18 HGV-infected liver tissues showed acute or mild chronic viral hepatitis with hepatocyte swelling, mitochondrial dilation, diminished or disappeared cristae, expansion of rough endoplasmic reticulum and loss of nucleoprotein granules. Intrahepatic lobules mild inflammatory cell infiltration. The results show that: HGV-induced liver disease may be significantly lighter than hepatitis A-E.