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目的由于抗生素作为控制感染性疾病的一大类药物,在临床上应用极为广泛和普遍,探究本院抗生素使用情况及预防措施。方法随机抽取内科住院处方1200张,外科住院处方1200张,观察抗生素不合理应用的比例。结果共抽取2400张处方,应用抗生素1～7种,平均每例患者使用抗生素0.84种,外科使用抗生素的种类1～4种,内科使用抗生素2～7种,共存在给药不合理有117例,其中重复给药37例,溶媒使用不合理29例,选药不合理21例,有配伍禁忌的2例,药物拮抗28例。结论做好医疗学生及低年资医师的培训,学习抗生素的合理应用,常规药敏实验,明确用药指证,发挥药师的临床指导作用。
Objective As antibiotics as a major category of drugs to control infectious diseases, the clinical application of a very wide and widespread, to explore the use of antibiotics in our hospital and preventive measures. Methods 1,200 inpatients were enrolled in the department of internal medicine and 1,200 inpatients in the surgical field. The proportion of unreasonable use of antibiotics was observed. Results A total of 2,400 prescriptions were drawn and 1 to 7 antibiotics were used. An average of 0.84 antibiotics per patient were used. There were 1 to 4 kinds of antibiotics used in surgery and 2 to 7 antibiotics used in medicine. There were 117 co-existing patients with unreasonable drug administration , Including repeated administration of 37 cases, unreasonable use of the drug in 29 cases, irrational drug selection in 21 cases, incompatibility in 2 cases, drug antagonism in 28 cases. Conclusion Good medical students and junior physicians training, learning the rational application of antibiotics, conventional susceptibility testing, a clear indication of drug use, pharmacists play a clinical guide.