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运动性哮喘(EIA)的机制目前尚不清楚,但认为其与运动后气道水分丢失局部渗透压升高有关[1],并认为部分原因是由于支气管微循环异常所致。为探讨局部高渗刺激后肺段内压力变化与肺血管通透性、25%~75%用力呼气流量/用力肺活量(FEF25%~75%/FVC)的关系,我们进行了相关实验研究。
The mechanism of exercise-induced asthma (EIA) is not yet clear, but it is believed that it is associated with an increase in the local osmotic pressure of airway loss after exercise [1] and is partly due to abnormal bronchial microcirculation. To investigate the relationship between intrapulmonary pressure changes and pulmonary vascular permeability after partial hypertonic stimulation, and 25% -75% forced expiratory flow / forced vital capacity (FEF25% -75% / FVC) relationship, we conducted relevant experimental studies.