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在反相高效液相色谱条件下,对抗孕激素RU 486和ZK 98734的色谱保留行为比较的结果,表明这两个药物的理化性质有显著的差别。对它们的理化性质,如:碱度、溶解度和分配系数分
The chromatographic retention behavior of the anti-progestins RU 486 and ZK 98734 under reversed-phase high-performance liquid chromatography showed significant differences in the physicochemical properties of the two drugs. Their physical and chemical properties, such as: alkalinity, solubility and partition coefficient