【摘 要】
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INTRODUCTIONrnIntervertebral disc (IVD) degeneration (IVDD) is one of the main causes of low back pain, which has been estimated as the top reason for years lived with disability globally.1 Current manage-ment strategies and treatments for IVDD are mainly
【机 构】
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Department of Orthopaedics,Union Hospital,Tongji Medical College,Huazhong University of Science and
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INTRODUCTIONrnIntervertebral disc (IVD) degeneration (IVDD) is one of the main causes of low back pain, which has been estimated as the top reason for years lived with disability globally.1 Current manage-ment strategies and treatments for IVDD are mainly focused on pain relief and cannot achieve fundamental and long-lasting therapeutic results.2 This is in part due to limited understanding of the pathogenesis of IVDD. Better understanding of the underlying pathological mechanisms of IVDD initiation, development and progression will help develop novel strategies for the prevention and treatments for this painful disease.
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