目的　探讨外照射慢性放射病 (简称慢放病 )患者免疫系统的远期变化。方法　对 16例慢放病患者确诊后三年随访中的感染情况、体液免疫和细胞免疫的观察。结果　发现患者免疫系统仍有不同程度的辐射损伤。结论　研究结果不仅指导患者的医疗保健 ,而且为慢放病远期恢复情况积累宝贵材料 Objective To investigate the long-term changes of the immune system in patients with chronic radiation sickness (referred to as slow-release disease). Methods The infection, humoral immunity and cellular immunity in 16 patients with slow-release disease were observed at three-year follow-up. The results showed that the patient’s immune system still have different degrees of radiation damage. Conclusions The findings not only guide the patient’s health care, but also accumulate precious materials for the long-term recovery of chronic illness