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目的:观察清胰利胆汤联合西医疗法治疗急性胆源性胰腺炎的临床效果。方法:选取120例湿热内蕴型急性胆源性胰腺炎患者作为研究对象,并按随机数字表法分为治疗组与对照组各60例,对照组给予常规治疗方案,治疗组在对照组治疗基础上加用清胰利胆汤治疗,比较2组患者中医证候评分、胰腺影像学形态及实验室指标[谷丙转氨酶(ALT)、碱性磷酸酶(ALP)、血淀粉酶(AMY)及尿淀粉酶(UAMY)]的改善情况。结果:治疗后,治疗组总有效率(91.67%)高于对照组(68.33%),2组比较,差异有统计学意义(P<0.05)。2组腹痛、上腹压痛感、腹胀、发热、恶心呕吐、嗳气、小便短赤、身目黄染评分较治疗前均有降低(P<0.05),治疗组各项评分均低于对照组(P<0.05)。2组CT影像学形态分级较治疗前均有改善(P<0.05),但2组间比较,差异无统计学意义(P>0.05)。2组ALP、ALT、AMY、UAMY水平较治疗前均降低(P<0.05),治疗组各项实验室指标值均低于对照组(P<0.05)。结论:在常规西药保守治疗基础上加用清胰利胆汤疏肝利胆、通腑泄热,可有效缓解湿热内蕴型急性胆源性胰腺炎患者的临床症状,改善胰腺影像学形态,更快地降低血、尿淀粉酶水平,临床疗效显著。
Objective: To observe the clinical effect of Qingyi Lidan combined with Western medical treatment of acute gallstone pancreatitis. Methods: A total of 120 patients with damp-heat intrinsic biliary pancreatitis were selected as study subjects and divided into treatment group (60 cases) and control group (60 cases) by random number table. The control group was given routine treatment. The treatment group Based on the addition of Qingyao Ligan Decoction, TCM syndrome scores, pancreas imaging morphology and laboratory indexes [ALT, ALY, AMY, And urinary amylase (UAMY)] to improve the situation. Results: After treatment, the total effective rate (91.67%) in the treatment group was higher than that in the control group (68.33%). There was significant difference between the two groups (P <0.05). The scores of abdominal pain, abdominal tenderness, abdominal distension, fever, nausea, vomiting, belching, shortness of urine and body yellow stain were lower than those before treatment in the two groups (P <0.05). The score of the treatment group was lower than that of the control group P <0.05). There was no significant difference between the two groups (P> 0.05) .2 The morphological classification of CT images in both groups improved compared with those before treatment (P <0.05). The levels of ALP, ALT, AMY and UAMY in the two groups were lower than those before treatment (P <0.05). The indexes in the laboratory were lower than those in the control group (P <0.05). Conclusion: Based on the conventional western medicine conservative treatment, adding Qingyi Lidan decoction can relieve the clinical symptoms of patients with damp-heat intrinsic biliary pancreatitis and improve the imaging features of the pancreas. Lower blood, urine amylase levels, clinical efficacy significantly.