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肠道微生态是人体最大、最复杂的微生态系统,其失衡与许多疾病的发生密切相关。调节肠道菌群失衡是治疗肠源性疾病的关键,其中粪菌移植已成功用于治疗难辨梭状芽孢杆菌感染、炎症性肠病、抗生素相关性腹泻和肠易激综合征等疾病。本文就粪菌移植的适应证、治疗效果、操作方法及存在问题等方面的研究进展作一综述。
Intestinal micro-ecology is the largest and most complex micro-ecosystem in the human body, and its imbalance is closely related to many diseases. Regulation of intestinal flora imbalances is the key to the treatment of gut-derived diseases, in which fecal transplants have been successfully used to treat diseases such as Clostridium difficile, inflammatory bowel disease, antibiotic-associated diarrhea and irritable bowel syndrome. This article reviews the indications, therapeutic effects, operation methods and existing problems of fecal bacteria transplantation.