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目的探讨替罗非班致严重不良反应的防治。方法分析替罗非班致急性重度血小板减少患者1例,对如何防治替罗非班致急性重度血小板减少提出合理化建议。结果替罗非班治疗急性非ST段抬高性心肌梗死患者可于1 h内出现重度血小板减少,停用后可逐渐恢复。结论替罗非班可致急性重度血小板减少症,应尽早监测血小板变化并及时处理,可预防严重不良事件的发生。
Objective To explore the prevention and treatment of serious adverse reactions induced by tirofiban. Methods One case of acute severe thrombocytopenia induced by tirofiban was analyzed in this study. The reasonable suggestions were given on how to prevent and treat acute severe thrombocytopenia caused by tirofiban. Results Tirofiban in patients with acute non-ST-segment elevation myocardial infarction in severe acute thrombocytopenia within 1 h, can gradually recover after withdrawal. Conclusion Tirofiban can induce acute severe thrombocytopenia, and platelet changes should be monitored as soon as possible to prevent serious adverse events.