Synthesis and Anti-HIV Activity of Trisubstituted (3'R, 4'R)-3',4'- Di-O-(S)-cam

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：queenie88

【摘要】

：

To further explore the potential of DCK analogs as anti-HIV drug candidates, ten new tri-substituted (3R,4R)-3,4-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) d

【作者】

：

Chun Hong ZHAO Ting ZHOU Lan X

【机构】

：

Beijing Institute of Pharmacology & Toxicology,Department of Chemistry,Beijing Institute of Microbio

【出处】

：

中国化学快报（英文版）

【发表日期】

：

2004年期

【关键词】

：

anti-HIV agent DCK analogs synthesis

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To further explore the potential of DCK analogs as anti-HIV drug candidates, ten new tri-substituted (3R,4R)-3,4-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives (4-13)were designed, synthesized, and evaluated against HIV replication in MT4 cells and H9 lymphocytes.

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Synthesis and Anti-HIV Activity of Trisubstituted (3'R, 4'R)-3',4'- Di-O-(S)-cam

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