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抗体依赖性细胞介导细胞毒作用(ADCC)在抗感染、移植免疫和肿瘤免疫以及自身免疫性疾病中可能起重要作用。因此在这些疾病中测定ADCC,无论在了解其免疫机制或临床应用上均有一定意义。据此,本文介绍了采用~(51)Cr释放试验测定ADCC的方法,并检测了正常人群及部分癌肿患者外周血中淋巴细胞的ADCC和探讨了影响
Antibody-dependent cell-mediated cytotoxicity (ADCC) may play an important role in combating infection, transplant and tumor immunity, and autoimmune diseases. Therefore, the determination of ADCC in these diseases, both in understanding its immune mechanism or clinical significance are of some significance. Accordingly, this article describes the use of ~ (51) Cr release assay for the determination of ADCC, and detection of normal population and some cancer patients with peripheral blood lymphocytes ADCC and explore the impact