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123例糖尿病人分为单纯糖尿病组和糖尿病合并高血压组,行动态血压监测,作颈动脉血管彩色多普勒超声测量颈动脉内膜-中膜厚度(IM T),IM T≥1.3mm判断为颈动脉硬化。同49例对照组进行对比研究。结果:单纯糖尿病组和糖尿病并高血压组的IM T较对照组明显增高,单纯糖尿病组的24h平均收缩压、夜间收缩压均较对照组明显增高(P<0.01),夜间收缩压、年龄与颈动脉粥样硬化相关。结论:糖尿病和高血压均为动脉粥样硬化的危险因素,糖尿病患者在合并高血压之前已出现血压异常,IM T和夜间收缩压是判断大血管硬化的较好方法。
123 cases of diabetic patients were divided into simple diabetic group and diabetic hypertension group, ambulatory blood pressure monitoring, carotid artery color Doppler ultrasound measurement of carotid intima - media thickness (IM T), IM T ≥ 1.3mm judgment Carotid atherosclerosis. With 49 cases of control group for comparative study. Results: Compared with control group, the IMT of diabetic group and diabetic and hypertensive group were significantly higher than those of control group. The mean systolic blood pressure and night systolic pressure of simple diabetic group were significantly higher than those of control group (P <0.01) Carotid atherosclerosis related. Conclusion: Diabetes mellitus and hypertension are the risk factors of atherosclerosis. Diabetic patients have abnormal blood pressure before hypertension. IM T and nighttime systolic pressure are the better methods to judge the severity of macrovascular disease.