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本实验采用高碘酸钠将细菌纤维素C6位的羟基氧化成醛基,同时利用醛基化合物与银氨络合物Ag(NH3)2+的反应,制备了纳米银/氧化细菌纤维素复合抑菌材料。分析了纳米颗粒的形成机制,考察了复合材料的银含量、表面形貌、纳米银粒径和结晶结构等;同时研究了复合材料对金黄色葡萄球菌的抑菌效果和对胎鼠表皮细胞增殖的影响。结果表明,AgNPs-DBC复合材料能抑制细菌的生长,同时不影响表皮细胞的正常增殖和分化,是一种潜在的创伤修复材料。
In this experiment, sodium periodate was used to oxidize the hydroxyl groups of C6 in bacterial cellulose to aldehyde groups. At the same time, the reaction of aldehyde compounds with Ag (NH3) 2 + Antibacterial material. The formation mechanism of nano-particles was analyzed, the silver content, surface morphology, size and crystal structure of nano-silver were investigated. The antibacterial activity of composite on Staphylococcus aureus and the proliferation of fetal rat epidermal cells Impact. The results showed that AgNPs-DBC composite could inhibit the growth of bacteria without affecting the normal proliferation and differentiation of epidermal cells, which was a potential wound repair material.