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达螨尽大鼠经口ＬＤ５０为１２４．３ｍｇ／ｋｇ（雌）、１１７．４ｍｇ／ｋｇ（雄）；小鼠经口ＬＤ５０为２８１．３ｍｇ／ｋｇ（雌）、２８９．０ｍｇ／ｋｇ（雄）；大鼠经皮ＬＤ５０＞２０００ｍｇ／ｋｇ（雌）、１５１０．８ｍｇ／ｋｇ（雄）；对家兔眼有轻度刺激作用，对皮肤无刺激；大鼠蓄积呈中等蓄积性；Ａｍｅｓ试验小鼠骨髓细胞微核试验和小鼠睾丸初级精母细胞遗传学效应试验均为阴性，未见诱变效应。
The oral LD50 of mites was 124.3 mg / kg (male) and 117.4 mg / kg (male) in mice. The oral LD50 of mice was 281.3 mg / kg (female) and 289.0 mg / kg Rat LD50> 2000mg / kg (female), 1510.8mg / kg (male); Rabbit eye mild stimulation, no stimulation of the skin; rat accumulation was moderate accumulation; Ames test mice Bone marrow cell micronucleus test and primary spermatocyte testis in mice testes were negative, no mutagenic effect.