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目的探讨米索前列醇联合葡萄糖酸钙对剖宫产术中和术后出血情况的临床疗效分析。方法将足月妊娠剖宫产产妇90例分成实验组和对照组,实验组(48例)于术前静脉注射葡萄糖酸钙,胎儿娩出后即给予米索前列醇舌下含化,对照组(42例)于娩出后立即给予米索前列醇含化并注射缩宫素。记录术中、术后2、12、24 h出血量及不良反应发生率。结果实验组术中及术后2、12、24 h出血量明显低于对照组,差异具有显著性统计学意义(P<0.01),实验组和对照组不良反应发生率比较差异无统计学意义(P>0.05)。结论米索前列醇联合葡萄糖酸钙可有效预防剖宫产产后出血。
Objective To investigate the clinical efficacy of misoprostol combined with calcium gluconate for cesarean section and postoperative bleeding. Methods Ninety cases of term pregnancy cesarean section were divided into experimental group and control group. The experimental group (48 cases) received intraoperative intravenous injection of calcium gluconate. The fetus was subacutely administered with misoprostol and the control group ( 42 cases) were given misoprostol immediately after delivery and oxytocin was injected. The intraoperative and postoperative 2,12,24 h bleeding and adverse reactions were recorded. Results The bleeding volume of the experimental group at 2, 12 and 24 h after operation was significantly lower than that of the control group (P <0.01), and there was no significant difference in the incidence of adverse reactions between the experimental group and the control group (P> 0.05). Conclusion Misoprostol combined with calcium gluconate can effectively prevent bleeding after cesarean section.