论文部分内容阅读
目的探讨取卵后卵子体外培养不同时间受精对体外受精-胚胎移植(IVF-ET)治疗患者实验室指标及临床指标是否有影响。方法选取2012年7月-2014年5月于该院生殖中心行IVF-ET治疗符合纳入标准的150例患者(150个周期)为研究对象,根据受精时卵子体外培养时间不同随机分为3组:2~4 h组(50例)、4~6 h组(50例)、>6 h(不超过7h)组(50例),比较3组间受精率、卵裂率,优质胚胎率、可用胚胎率及妊娠率、种植率、流产率是否有差异。结果分别比较3组患者的MII卵受精率、正常受精率、正常卵裂率、优质胚胎率、可用胚胎率、临床妊娠率、着床率及流产率,差异均无统计学意义(P>0.05)。结论 IVF-ET治疗中卵子体外培养不同时间(2~7 h)受精对实验室指标及临床结局无明显影响。
Objective To investigate whether the fertilization of ovum oocytes after in vitro fertilization at different times has any influence on the laboratory and clinical indexes of IVF-ET patients. Methods A total of 150 patients (150 cycles) eligible for IVF-ET at the reproductive center of our hospital from July 2012 to May 2014 were enrolled in this study. According to the time of in vitro fertilization, the eggs were randomly divided into three groups (N = 50), 4 ~ 6 h group (n = 50) and> 6 h (no more than 7 h) group (n = 50). The fertilization rate, cleavage rate, Available embryos and pregnancy rates, implantation rates, abortion rates are different. Results There were no significant differences in fertilization rate, normal fertilization rate, normal cleavage rate, high quality embryo rate, available embryo rate, clinical pregnancy rate, implantation rate and abortion rate among the three groups (P> 0.05 ). Conclusion IVF-ET treatment in vitro fertilization of eggs at different times (2 ~ 7 h) fertilization on laboratory parameters and clinical outcome no significant effect.