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利用机械合金化和在1150°C、氩保护气氛下退火2 h制备生物玻璃纳米复合材料。采用银对Ti-45S5生物玻璃进行化学改性。研究含银Ti-10%45S5生物玻璃纳米复合材料对变异链球菌和金黄色葡萄球菌的抗菌活性。使用XRD、SEM-EDS、TEM对纳米复合材料的相组成、晶体结构和晶粒尺寸进行表征。体外细菌粘附研究表明,在纳米结构Ti-45S5生物玻璃表面的变异链球菌和金黄色葡萄球菌数量比微晶钛板表面的显著减少。钛基纳米结构生物材料将是下一代牙移植材料。
Bioglass nanocomposites were prepared by mechanical alloying and annealing at 1150 ° C under an argon atmosphere for 2 h. Ti-45S5 bioglass was chemically modified with silver. To study the antibacterial activity of silver-containing Ti-10% 45S5 bioglass nanocomposites on S. mutans and S. aureus. The phase composition, crystal structure and grain size of nanocomposites were characterized by XRD, SEM-EDS and TEM. In vitro bacterial adhesion studies show that the number of S. mutans and S. aureus on the surface of nanostructured Ti-45S5 bioglass is significantly reduced compared to the surface of microcrystalline Ti. Titanium-based nanostructured biomaterials will be the next generation of dental implants.