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目的通过对抗感染药不良反应报告的分析,探讨不良反应发生的因素。方法对2008年度收集到的136例抗感染药致不良反应报告进行回顾性分析。结果涉及不良反应的药品共有36种,其中以头孢菌素类居首,其次是喹诺酮类;最常涉及皮肤系统,静脉给药引起的不良反应最多。结论应加强抗感染药不良反应监测,合理使用抗感染药,为保障公众用药健康服务。
Objective To analyze the adverse reaction reports of anti-infectives and explore the factors of adverse reactions. Methods A retrospective analysis was conducted on the adverse reactions of 136 anti-infectives collected in 2008. Results There were 36 kinds of drugs involving adverse reactions, among which cephalosporins and quinolones were the second most common drugs. The skin reactions were most frequently caused by intravenous injection. Conclusion Adverse reaction monitoring of anti-infectives should be strengthened, anti-infectives should be used reasonably, and health services for public use should be guaranteed.