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本文对185名正常初产孕妇的血清叶酸水平、缺乏情况以及与婴儿出生体重的关系进行了研究。结果表明,血清叶酸水平随妊娠周数的增加呈下降趋势,孕中期、末期与早期相比,血清叶酸浓度明显降低,有显著差别。血清叶酸低于3ng/ml人数所占百分比由早期8.5％、中期9.7％至末期升至31.3％,三期共计31例,占总观察人数的16.8％。 对127名孕妇妊娠末期叶酸水平与婴儿出生体重的关系进行了分析,按婴儿出生体重分三组,母亲叶酸水平各组无显著差异。另对30名婴儿出生体重超过4000g的母亲,于产后24小时内取血测血清叶酸,结果与上述三种不同出生体重组母亲血清叶酸浓度亦无明显差别。本次研究未观察到孕期血清叶酸水平与婴儿出生体重之间有相关。
In this paper, 185 normal primiparous pregnant women serum levels of folic acid, the lack of conditions and the relationship with the birth weight of infants were studied. The results showed that the level of serum folate decreased with the increase of gestational weeks, and the levels of serum folate were significantly lower than those in early, middle and late pregnancy, with significant differences. The percentage of patients with serum folic acid below 3 ng / ml increased from 8.5% in the early stage to 9.7% in the end to 31.3% in the end, with a total of 31 cases in the third phase accounting for 16.8% of the total. The relationship between folic acid levels and birth weight of 127 pregnant women at the end of pregnancy was analyzed. There were no significant differences in folate levels among the three groups according to their birth weight. Another 30 babies born more than 4000g weight of mothers within 24 hours after childbirth to take blood serum folate, the results and the above three different birth weight mothers serum folic acid concentration there was no significant difference. This study did not observe a correlation between serum folate levels during pregnancy and infant birth weight.